The San Francisco 49ers are 10-4 and travel to face the Indianapolis Colts on Monday. We break down how they can clinch a ...

Playoff fantasy implications loom as 49ers clash with Colts. Identify your waiver wire heroes and crucial lineup decisions ...

The 49ers (10-4) face NFL rushing leader Jonathan Taylor and unretired QB Philip Rivers on Monday night in Indianapolis ...

The 2025 draft class is starting to look disappointing for the San Francisco 49ers. On Saturday, the Niners placed rookie ...

San Francisco 49ers wide receiver Brandon Aiyuk hasn't been on the field this year, but he's been a frequent topic of ...

For the second time since they traded him, the San Francisco 49ers will face DeForest Buckner and the Indianapolis Colts. Or ...

Aiyuk hasn't played for the 49ers all season but drove by the team facilities in a video posted to his YouTube account.

San Francisco 49ers wide receiver Ricky Pearsall will miss Monday night's game against the Indianapolis Colts after ...

The San Francisco 49ers will go into a vital Monday Night Football matchup vs. the Indianapolis Colts without two starters.

Colts coach Shane Steichen said starting DT DeForest Buckner will make his return Monday night vs the 49ers after missing 5 ...

The Indianapolis Colts released their final injury report ahead of a crucial Monday Night game against the San Francisco ...

The 49ers wide receiver Brandon Aiyuk hasn't played in 2025. But now an alarming video has drawn concerns from fans.