The San Francisco 49ers are 10-4 and travel to face the Indianapolis Colts on Monday. We break down how they can clinch a ...

Playoff fantasy implications loom as 49ers clash with Colts. Identify your waiver wire heroes and crucial lineup decisions ...

Find single game tickets to the San Francisco 49ers vs. Indianapolis Colts NFL Week 16 matchup on Monday, December 22, 2025 ...

The San Francisco 49ers cannot just walk into Indianapolis and beat the Colts without putting in a good effort; their roster ...

The Indianapolis Colts have gone 1-5 in their last six games. Key players at impact positions are now out, and the team is ...

It wasn't just the Seahawks celebrating Thursday's night win. The 49ers now have a path to the NFC West title, too.

Here's a look at the studs and duds (and those in between) from the Tennessee Titans' 37-24 loss to the San Francisco 49ers ...

SANTA CLARA, Calif. (AP) — Brock Purdy threw three touchdown passes and the San Francisco 49ers started the stretch run of ...

Tight end George Kittle's wife has partnered with Smirnoff to continue bringing high spirits to the suite amid all the NFL ...

A lot of the 49ers' biggest contributors weren't on the team last year. Heck, some of them weren't even on the team in Week 1 ...

For NFL WAG Sydney Warner, football season is about as busy as it can get this year. With her husband, San Francisco 49ers ...

Highlighting the San Francisco 49ers interns, their career paths, roles within the organization, and advice for aspiring ...