DNA-encoded chemical library - Wikipedia
DNA-encoded chemical libraries (DECL) is a technology for the synthesis and screening on an unprecedented scale of collections of small molecule compounds. DECL is used in medicinal …
DNA-Encoded Chemical Libraries: A Comprehensive Review with …
DNA-encoded chemical libraries (DELs) represent a versatile and powerful technology platform for the discovery of small-molecule ligands to protein targets of biological and pharmaceutical …
Small-molecule discovery through DNA-encoded libraries - Nature
Jun 16, 2023 · Within the past 15 years, DNA-encoded library (DEL) technology has matured into a widely used platform for small-molecule discovery, yielding a wide variety of bioactive …
Challenges and Prospects of DNA-Encoded Library Data …
Nov 7, 2024 · DNA-encoded library (DEL) technology is a powerful platform for the efficient identification of novel chemical matter in the early drug discovery process enabled by parallel …
Recent advances in DNA-encoded libraries - RSC Publishing
Jun 23, 2025 · The DNA-encoded library (DEL), a novel high-throughput screening platform that synergistically combines the strengths of combinatorial chemistry and genetic barcoding, has …
Future of Drug Discovery with DNA Encoded Libraries
One ground-breaking solution that has emerged in recent years is the utilization of DNA-encoded libraries (DELs). DELs stand as a versatile and potent technology foundation for uncovering …
DNA-encoded libraries (DELs): a review of on-DNA chemistries …
A DNA-encoded library is a collection of small molecules covalently linked to DNA that has unique information about the identity and the structure of each library member.
Highly pure DNA-encoded chemical libraries by dual-linker
Jun 13, 2024 · DNA-encoded chemical libraries enable screening of an enormous number of prospective drug compounds in parallel. The idea is that the functional components of each …
Evaluation of DNA encoded library and machine learning model ...
Apr 2, 2025 · DNA-Encoded Library (DEL) technology allows the screening of millions to billions of compounds in a pooled fashion, which is faster and cheaper than traditional approaches.
DNA-Encoded Libraries (DEL) - WuXi Biology
DNA-Encoded Library (DEL) technology involves a novel affinity selection process that integrates chemistry, biology, bioinformatics and computational chemistry to facilitate a rapid drug …