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  1. Transforming growth factor - Wikipedia

    The name transforming growth factor is somewhat arbitrary because the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor …

  2. TGF-β signaling in health, disease and therapeutics

    Mar 22, 2024 · Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can stimulate diverse …

  3. TGF-beta signal transduction: biology, function and therapy for ...

    Dec 22, 2022 · The transforming growth factor beta (TGF-β) is a crucial cytokine that get increasing concern in recent years to treat human diseases. This signal controls multiple …

  4. TGF-β signaling in health and disease: Cell

    Sep 14, 2023 · Here, we review how TGF-β coordinates multicellular response programs in health and disease and how this knowledge can be leveraged to develop treatments for diseases of …

  5. Transforming growth factor beta - Wikipedia

    TGF-beta is a cytokine with three different isoforms, which regulates many cellular functions including cell proliferation, differentiation, adhesion and migration.

  6. Transforming Growth Factor - an overview | ScienceDirect Topics

    Transforming growth factor (TGF) is defined as a member of a superfamily of growth factors that modulate various processes involved in embryonic development and organogenesis, including …

  7. TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and …

    The transforming growth factor-β (TGF-β) is the prototype of the TGF-β family of growth and differentiation factors, which is encoded by 33 genes in mammals and comprises homo- and …

  8. What Does TGF Beta Do? Roles in Growth, Repair, and Health

    Apr 29, 2025 · Transforming Growth Factor Beta (TGF-β) is a multifunctional protein that regulates cell behavior, tissue development, and immune responses. While essential for …

  9. Transforming growth factor-β receptors: versatile mechanisms

    Feb 13, 2024 · Transforming growth factor-β (TGF-β) signaling is initiated by activation of transmembrane TGF-β receptors (TGFBR), which deploys Smad2/3 transcription factors to …

  10. TGF alpha - Wikipedia

    TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This …